The Mouse Casc5 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to CT29, D40, and KNL1. This antibody recognizes Mouse antigen. The Mouse Casc5 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity)